Effects of a comprehensive intervention on hypertension control in Chinese employees working in universities based on mixed models

Yang Li,Yan Jing,Yu Wei,Wang Xin,Wang Zengwu,Xu Xiaoling,Zheng Pinpin,Shou Xiaoling,Jin Xiaoqing,Tang Xinhua

doi:10.1038/s41598-019-55849-6

Abstract

We conducted a comprehensive intensive intervention for hypertension patients working in universities or colleges. From July 2015 to March in 2016, 220 hypertension subjects were recruited, with 165 cases in intensive intervention group and 55 in standard intervention group. After 24 months of intervention, 208 ones including of 157 in intensive intervention group and 51 in standard intervention group were included in the final analysis. The patients in standard intervention group were given routine intervention, which mainly including of drug treatment and health education. The patients in intervention group were given comprehensive intensive intervention in addition to routine intervention, including follow-up management of hypertension, emotional, lifestyle intervention and else. The study and experimental protocols were approved by institutional review board of Zhejiang Hospital and Fu Wai Hospital and registered (ChiCTR-ECS-14004641, date of registration: May 8, 2014). After 2 years, compared with the standard intervention group, SBP/DBP in the intensive intervention group decreased by 3.7/4 mmHg and BP control rate increased by 8.9%, and the unhealthy behaviors and life quality including tension and pressure were also improved in the intensive intervention group. We used mixed effect model to analyze the intervention effect which could solve the problems of missing values and correlation. The intensive intervention of hypertension control including follow-up management, emotional and lifestyle intervention in occupational places could promote the development of the prevention, treatment and control of hypertension among staff in colleges and universities.

Highlights

We conducted a comprehensive intensive intervention for hypertension patients working in universities or colleges
According to the Chinese guidelines for prevention and control of hypertension in 2010, and the policy statement on implementing workplace health programs to prevent cardiovascular disease issued by the American heart association (AHA)[9,10], we developed the comprehensive intensive intervention for hypertension control, which considering of the actual situation in the workplace
Among the risk factors related to cardiovascular disease, vegetable consumption increased by 2 g/day, fruit consumption increased by 2.1 g/day, regular exercise increased by 1.2 times/week, smoking rate decreased by 7.5%, drinking rate decreased by 31%, and the mean score of MINICHAL decreased by 10.4

Summary

Introduction

We conducted a comprehensive intensive intervention for hypertension patients working in universities or colleges. The intensive intervention of hypertension control including follow-up management, emotional and lifestyle intervention in occupational places could promote the development of the prevention, treatment and control of hypertension among staff in colleges and universities. Most adults aged 30–60 are belonged to occupational groups, they spend about 1/3 of their waking hours in work places Their health is closely related to social stability and development. Among the www.nature.com/scientificreports occupational population, college employees, mainly intellectuals, have been responsible for teaching and scientific research for long time Many comprehensive factors, such as heavy tasks, mental tension, psychological pressure, lack of exercise and neglect of health care, lead to high BP, making them vulnerable to hypertension. We aimed to provide a suitable way to control hypertension for occupational population, and evaluate the comprehensive intensive intervention for hypertension patients working in universities or colleges

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