Effects of a 2-hour run on metabolic economy and lower extremity strength in men and women.

Abstract

Changes in running economy, or the oxygen cost of running at a given submaximal speed (ml/m/kg), during prolonged exercise have been well described in men but not in women. Lower extremity strength changes associated with prolonged exercise have never been addressed. We examined changes in running economy and strength following a 2-hour run in eight men and eight women. Knee and hip strength were measured pre- and post-running. Peak oxygen consumption (VO2peak) and oxygen consumption at ventilatory threshold were determined. Subjects then ran for 2 hours at an intensity which elicited ventilatory threshold (68.7% vs. 66.6% of VO2peak for men and women, p = 0.5). Water was ingested at a rate of 0.5% of body weight each half hour. Oxygen uptake (VO2) and respiratory exchange ratio were measured initially and at 1 and 2 hours. Body weight declined in the men (p = 0.001) but not in the women (p = 0.12). Running economy decreased in the men (p < 0.001) but not in the women (p = 0.084). At 2 hours of running, knee flexion and extension strength declined significantly in the men only (effect of gender x time, p < 0.014), but hip flexion, abduction, and adduction strength declined in both genders. Decreased knee extensor/flexor strength was evident in men only, while decreased hip strength was independent of gender. We conclude that 2 hours of running produced changes in knee strength and running economy in men only.