Abstract

BackgroundGestational diabetes mellitus (GDM) emerges worldwide and is closely associated with short- and long-term health issues in women and their offspring, such as pregnancy and birth complications respectively comorbidities, Type 2 Diabetes (T2D), metabolic syndrome as well as cardiovascular diseases. Against this background, mobile health applications (mHealth-Apps) do open up new possibilities to improve the management of GDM. Therefore, we analyzed the clinical effectiveness of specific mHealth-Apps on clinical health-related short and long-term outcomes in mother and child.MethodsA systematic literature search in Medline (PubMed), Cochrane Library, Embase, CINAHL and Web of Science Core Collection databases as well as Google Scholar was performed. We selected studies published 2008 to 2020 analyzing women diagnosed with GDM using specific mHealth-Apps. Controlled clinical trials (CCT) and randomized controlled trials (RCT) were included. Study quality was assessed using the Effective Public Health Practice Project (EPHPP) tool.ResultsIn total, n = 6 publications (n = 5 RCTs, n = 1 CCT; and n = 4 moderate, n = 2 weak quality), analyzing n = 408 GDM patients in the intervention and n = 405 in the control groups, were included. Compared to control groups, fasting blood glucose, 2-h postprandial blood glucose, off target blood glucose measurements, delivery mode (more vaginal deliveries and fewer (emergency) caesarean sections) and patient compliance showed improving trends.ConclusionmHealth-Apps might improve health-related outcomes, particularly glycemic control, in the management of GDM. Further studies need to be done in more detail.

Highlights

  • Gestational diabetes mellitus (GDM) emerges worldwide and is closely associated with short- and long-term health issues in women and their offspring, such as pregnancy and birth complications respectively comorbidities, Type 2 Diabetes (T2D), metabolic syndrome as well as cardiovascular diseases

  • In detail, compared to control groups, fasting blood glucose, 2-h postprandial blood glucose, off target blood glucose measurements, delivery mode (more vaginal deliveries and fewer caesarean sections) and patient compliance improved by using Mobile health (mHealth)-apps in GDM care

  • We found only a few randomized controlled trials (RCT) and clinical trials (CCT) evaluating the clinical effectiveness of GDM specific mHealth-Apps

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Summary

Introduction

Gestational diabetes mellitus (GDM) emerges worldwide and is closely associated with short- and long-term health issues in women and their offspring, such as pregnancy and birth complications respectively comorbidities, Type 2 Diabetes (T2D), metabolic syndrome as well as cardiovascular diseases Against this background, mobile health applications (mHealth-Apps) do open up new possibilities to improve the management of GDM. 2.1% and Having the concept of transgenerational programming (“fetal or perinatal programming”) in mind, intra-uterine exposure to hyperglycemia “programs” the offspring to eg, obesity, glucose intolerance, T2D, insulin resistance, metabolic syndrome, high blood pressure, and Eberle et al BMC Pregnancy and Childbirth (2021) 21:808 cardiovascular diseases [6,7,8,9,10] In this context, early strategies are needed to improve the management of GDM effectively. We systematically reviewed studies that evaluated the effectiveness of GDM specific mHealth-Apps on health-related outcomes in GDM patients compared to control groups

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