Abstract
In a recent 8-year period since January 1989, 29 patients with perforation of the colon were treated at the department. The leukocyte count, platelet count, and urea nitrogen concentration up to postoperative day 7 were compared according to systemic inflammatory response syndrome (SIRS) status. Group I (7 patients) was negative for SIRS. Group II (13 patients) was positive for SIRS and Group II patients were subdivided into group II-1, consisting of eight survivors and group II-2, consisting of five patients who died. Group III (9 patients) was positive for SIRS and underwent PMX. As compared with thepreoperative leukocyte counts in group I (7400 ± 4100/mm3) and group II (8800 ± 6600/mm3), the value in group II-1 (12900 ± 1600/mm3) was high and those in group II-2 (2400 ± 1600/mm3) and group III were very low (2500 ± 1200/mm3). Postoperatively, however, the leukocyte count increased with time to 9800 ± 4300/mm3 on postperative day 7 in patients who underwent PMX, which was significantly higher than the value in group II-2. Similar trends were seen for the platelet count and urea nitrogen concentration. Our results suggest that PMX is effective for improving the status of patients who are positive for SIRS.
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Schedule a callMore From: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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