Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial

Miriam Santer,Megan Lawrence,Susanne Renz,Zina Eminton,Beth Stuart,Tracey H Sach,Sarah Pyne,Matthew J Ridd,Nick Francis,Irene Soulsby,Karen Thomas,Natalia Permyakova,Paul Little,Ingrid Muller,Jacqui Nuttall,Gareth Griffiths,Kim S Thomas,Alison M Layton

doi:10.1136/bmj-2022-074349

Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial

Miriam Santer, Megan Lawrence + Show 16 more

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https://doi.org/10.1136/bmj-2022-074349

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Journal: BMJ	Publication Date: May 16, 2023
Citations: 12	License type: open-access

Affiliation: Norwich Research Park, University of Southampton, Queen Mary University of London, University of Nottingham, University of Bristol, Hull York Medical School

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Abstract

ObjectiveTo assess the effectiveness of oral spironolactone for acne vulgaris in adult women.DesignPragmatic, multicentre, phase 3, double blind, randomised controlled trial.SettingPrimary and secondary healthcare, and advertising in the community and...

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