Effectiveness of smoking cessation interventions for smokers with Crohn's disease: a systematic review.

Abstract

Smoking cessation (SC) in Crohn's disease (CD)is widely accepted to be the most important modifiable factor to improve outcomes in these patients. We aimed in this review to provide a summary of the evidence base regarding the effectiveness of SCinterventions in patients with CD. The following databases were systematically searched from inception to February 2022: PubMed, Google Scholar and Cochrane Library. Overall, five articles met the research criteria. Studies sample size ranged from 17 to 474 patients. At the outcome level, the abstinence rates ranged from 14.8to 42% and was ≤25% in four studies. The three studies with control groups did not report statistically higher SC rates in the intervention groups. No predictors of interventions success were identified in this review. Implementation and evaluation of tailored SC interventions for CD patients must be promptly addressed in further studies.