Abstract

Paediatric migraine headache is a common condition for which there is no general consensus on the choice of prophylactic. Riboflavin has been considered as a potential prophylactic which is well tolerated. This review examines the current literature regarding the efficacy of riboflavin as a prophylactic. There have been mixed results from both retrospective studies as well as randomised controlled trials. Whilst the adverse effect profile is minimal compared to other migraine prophylactics, further well-designed studies with larger sample sizes and longer follow-up are required.

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