Abstract

A subgroup analysis of the EORTC trial was performed and long-term survival determined. From 341 patients, 149 (median age 52 years, 18-69) were identified with macroscopic complete resection (R0, R1) of abdominal and retroperitoneal soft-tissue sarcomas (median diameter 10 cm, G2 48.3%, G3 51.7%). 76 patients were treated with EIA (etoposide, ifosfamide, doxorubicin) + RHT (>= 5 cycles: 69.7%) vs. 73 patients receiving EIA alone (>= 5 cycles: 52.1%, p=0.027). LPFS and DFS as well as overall survival were determined. 1437P | Effectiveness of Regional Hyperthermia with Chemotherapy for High-risk Retroperitoneal and Abdominal Softtissue Sarcoma after Complete Surgical Resection: A Subgroup Analysis of a Randomized phase-III Multicenter Study

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