Effectiveness of profile by Sanford behavioral weight loss program for weight loss following endometrial cancer treatment

Abstract

ObjectiveTo examine differences in weight change and Body Mass Index (BMI) at 12 months among women in remission from endometrial cancer who enrolled in a behavioral weight loss (BWL) program and a matched patient control group. MethodsWomen (n = 22) were enrolled into the BWL program and were compared against a control group (n = 28) that accounted for age, BMI, cancer type, cancer stage, and treatment dates. The BWL program included weekly health coaching meetings that targeted nutrition, activity, and behavior change topics. ResultsWomen enrolled in the BWL program completed 28.3 ± 14.1 appointments over 12 months resulting in an average weight change of −14.2 ± 7.8 kg (−13.3 ± 7.4%) at 6 months and −16.4 ± 12.5 kg (−15.3 ± 11.4%) at 12 months (all p < 0.001). Women in the control group had a weight change of −1.7 ± 8.4 kg (−2.3 ± 7.6%) at 12 months which was significantly different than the BWL condition (p < 0.001). BMI was significantly reduced in the BWL group at 6 months (−4.8 ± 4.5, p < 0.001) and 12 months (−5.2 ± 5.9, p < 0.001) and significantly different than in the control group at 12 months (−0.9 ± 3.2, p = 0.007). ConclusionsThe BWL program yielded clinically significant weight loss for endometrial cancer survivors. Future work should include longer follow up periods and include additional behavioral and psychosocial outcomes.