Effectiveness of Passiflora foetida (Baby Semitoo) and Ocimum campechianum extracts (Married Man Pork) against Pseudomonas aeruginosa and Klebsiella pneumoniae

Abstract

Abstract. Scott S, Daniel R, Kalicharran L. 2023. Effectiveness of Passiflora foetida (Baby Semitoo) and Ocimum campechianum extracts (Married Man Pork) against Pseudomonas aeruginosa and Klebsiella pneumoniae. Asian J Nat Prod Biochem 21: 79-87. Medicinal plants have long been used to treat illnesses. They contain many secondary metabolites, which have antibiotic properties, and can treat antimicrobial resistance in bacteria. The aim of this study was to investigate the phytochemicals in Passiflora foetida L. (Baby Semitoo) and Ocimum campechianum Mill. (Married Man Pork) and to analyze the antimicrobial potential against Klebsiella pneumoniae and Pseudomonas aeruginosa. Plant extracts were prepared using hexane, methanol, and water, with a rotary evaporator. The extracts were tested using zone of inhibition, Minimum Inhibitory Concentration (MIC), and Minimum Bacterial Concentration (MBC) methods. The extract of O. campechianum produced the highest percent yield for each solvent, while methanol produced the highest yield of all solvents. The results of the phytochemical test showed that, O. campechianum contained flavonoids, tannins, saponins, glycosides, and phenols; while flavonoids, tannins, glycosides, and saponins were found in P. foetida extract. Similarly, O. campechianum also showed higher antimicrobial potential than P. foetida. The P. aeruginosa proved more susceptible than K. pneumoniae to both plants.