Abstract
The purpose of this study was to analyze the effect of giving papaya leaf extract (Carica papaya) and the most effective dose in inhibiting Aeromonas hydrophila bacterial infection in Koi (Cyprinus rubrofuscus). This research is an experimental study with four treatments: Control Treatment (K): 0 ppm, Treatment A: 1000 ppm, Treatment B, and Treatment C: 1400 ppm. Data were processed using SPSS Version 24 with Analysis (ANOVA) and Kruskal-Wallis H. The results showed that giving papaya leaf extract had an effect on inhibiting Aeromonas hydrophila bacterial infection in koi. The condition of the fish improved on the 7th day after immersion; it was shown that the way they swam began to return to normal, and the clinical symptoms reduced due to infection. The lowest inhibition level was in the control treatment, the condition of the fish worsened every day, and the highest survival was in treatment B, namely 86.67%, the average behavior scale is 5.00, and the average morphological scale is 5.00. The average water quality temperature is 27.2-28.1˚C, the average pH is 7.1-7.2, the average dissolved oxygen is 5.7-5.8 ppm, and the ammonia is 0.25 ppm.
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