Effectiveness of nasal continuous airway pressure therapy in patients with obstructive sleep apnea.

Abstract

A prospective observational study was carried out with the aim of evaluating the effectiveness of nasal continuous positive airway pressure (nCPAP) therapy on the health-related quality of life (QoL) of patients with obstructive sleep apnea (OSA). The patients included in this study were those recently diagnosed with OSA (AHI>5) and given nCPAP therapy, as well as being referred to a sleep laboratory for an assessment of their sleep disordered breathing. Prior to the start of nCPAP therapy and polysomnography evaluation, patients were asked to complete the validated Quebec sleep questionnaire (QSQ), and their baseline measurements were recorded. Among the study population, 14.41% (n=31) had mild OSA with an apnea and hypopnea index of 5 to 14.9 events/h, while 26.97% (n=58) had moderate OSA and 40% (n=86) had severe OSA. The overall average apnea and hypopnea index of the study population was 30.24±9.73 events/h; mild OSA patients had an average apnea and hypopnea index of 10.09±2.65 events/h, moderate OSA patients had 21.48±4.40 events/h, and severe OSA patients had 59.16±22.14 events/h. A significant difference was observed between the scores before treatment and after 6months of therapy in all domains of the QSQ QoL scores (P<0.0001). Nasal continuous positive airway pressure treatment improved the QoL for patients with mild, moderate, and severe sleep apnea.