Abstract
Aims and Objective: To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated , group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.
Highlights
Cadmium (Cd) is an environmental element with a broad range of applications in the industry.[1]
Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium
Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms
Summary
Cadmium (Cd) is an environmental element with a broad range of applications in the industry.[1]. It is believed that this particular medicinal preparation is highly effective for inflammation and infections, cardiac related ailments, digestive disorders, as well as liver diseases. It is one of the best natural coagulant discovered so far as it causes an increase in the platelet count.[13] studies have shown that MOE battles cadmium induced metal intoxication, scientific literature is devoid of findings regarding the effect of MOE on the platelet count in cadmiumexposed rats. Current experiments were designed to investigate the effect of MOE on total plateletcount on adult Wistar Albino rats exposed to cadmium
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