Abstract
Background Osteoarthritis is becoming a global major cause of pain and functional disability worldwide, especially in the elderly population. Nowadays, evidence shows that mobilization with movement (MWM) has a beneficial effect on knee osteoarthritis subjects. However, its adequacy remains unclear. Objective To review the best available evidence for the effectiveness of MWMs on pain reduction and functional improvement in patients with knee osteoarthritis. Methods A comprehensive search of literature was conducted using the following electronic databases: Google Scholar, PubMed, Physiotherapy Evidence Database (PEDro), Science Direct, Cochrane Library, and Scopus. Only randomized controlled trials (RCTs) were included, and the methodological quality of the studies was appraised using the PEDro scale. It was reported according to the guideline of the PRISMA statement. Results A total of 15 RCTs having 704 participants were included. The present systematic review suggests that there were significant differences between MWM groups and control groups in terms of visual analogue scale (VAS), Western Ontario and MacMaster Universities Osteoarthritis Index (WOMAC) scale, and flexion range of motion. Conclusions This systematic review demonstrated that MWM was effective to improve pain, range of motion, and functional activities in subjects with knee osteoarthritis.
Highlights
Osteoarthritis (OA) is a chronic degenerative disease characterized by the deterioration of the cartilage in the joints, creating stiffness, pain, and impaired movement [1, 2]
Systematic and comprehensive searches were conducted in electronic databases such as Google Scholar, Physiotherapy Evidence Database (PEDro), Scopus, Science Direct, Cochrane Library, and PubMed. e search was made using the following keywords: mobilization with movement, knee osteoarthritis, and randomized controlled trial
As the topic titles speckled among the databases, various combinations of the keywords were used: “Mulligan’s mobilization/mobilization with movement/sham/placebo mobilization with movement” and “osteoarthritis/knee joint pain/Arthritis/ degenerative knee arthritis” and “randomized controlled trial.”
Summary
Osteoarthritis (OA) is a chronic degenerative disease characterized by the deterioration of the cartilage in the joints, creating stiffness, pain, and impaired movement [1, 2]. Osteoarthritis a leading cause of pain and functional disability in both developed and developing countries, especially in the elderly population [3, 4]. E knee joint is the most commonly affected joint by OA due to its weight-bearing requirement, high mobility, and lack of intrinsic stability [5] It leads to limitations in activities of daily life and impairment in the quality of life because of the accompanying pain and morning stiffness in the joint [6]. To review the best available evidence for the effectiveness of MWMs on pain reduction and functional improvement in patients with knee osteoarthritis. Is systematic review demonstrated that MWM was effective to improve pain, range of motion, and functional activities in subjects with knee osteoarthritis Conclusions. is systematic review demonstrated that MWM was effective to improve pain, range of motion, and functional activities in subjects with knee osteoarthritis
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