Abstract
Purpose: To review the effectiveness and underlying mechanism of different types of psychotherapy to improve medication adherence (MA).Methods: In this review, the status and possible factors influencing medication adherence in patients with depression patients based on information obtained from various literature.Results: Although the focus of psychologists' analysis of the causes and solutions of mental illness is different, several of these therapies can improve patient compliance with their medications. An effective psychotherapy can change patients’ attitudes towards disease and help them reduce the disease recurrence rate.Conclusion: Psychotherapy has an irreplaceable role in dealing with the major depressive disorder. This review aimed to provide effective instructions for improving medication adherence and reducing disease relapse and recurrence in the future.
 Keywords: Depression, Medication adherence, Psychotherapy
Highlights
Major depressive disorder (MDD) is a common psychiatric disease, and poor medication adherence (MA) is one of the most serious problems in those patients
Systematic treatment is recommended for depression, and those MDD should take long-term or even life-long medications to avoid recurrence
Cognitive behavioral therapy (CBT) is well documented psychosocial treatment in psychiatry. It is the combination of cognitive therapy (CT) and behavior therapy (BT), which is based on the belief that people’s behavior is deeply influenced by their automatic negative thoughts
Summary
Major depressive disorder (MDD) is a common psychiatric disease, and poor medication adherence (MA) is one of the most serious problems in those patients. Optimal treatment often includes a combination of therapy and antidepressant medication. Systematic treatment is recommended for depression, and those MDD should take long-term or even life-long medications to avoid recurrence. Patients who discontinue treatment can cause recurrence and increase treatment difficulty. The research shows that the recurrence of discontinued treatment is twice as long as continued treatment [1]. Whether to follow the doctor’s advice and treatment scheme is an important factor affecting the recurrence rate. According to a previous investigation,over 50 % MDD patients who stay in treatment exhibit poor MA [2]. The reasons behind the phenomenon include both patient and clinician factors [3]
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