Abstract
Synopsis The effectiveness of macrogol and talcum base formulations of a new multi-insect repellent N, N-diethyl phenyl acetamide (DEPA) was studied against Aedes aegypti mosquitoes in the laboratory. The efficacy was compared with widely used repellent in India, viz. Dimethylphthalate. Twenty-five per cent DEPA incorporated macrogol ointment and talcum base formulation offered more than 8 h and 6 h protection, as compared to DMP for 3 h and 1 h 30 min, respectively. The ointment was found to be stable as more than 99% DEPA was recovered by gas liquid chromatography after 6 months of storage at room temperature. The repellent formulations have not shown any gross adverse effect to the skin of albino rabbits.
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