Abstract
Review question/objective The objective of this review is to identify the effectiveness of ketamine gargle in comparison to placebo in reducing postoperative sore throat for patients undergoing airway instrumentation. Inclusion criteria Types of participants This review will consider studies that include all patients over the age of four with the ability to gargle safely who are undergoing airway instrumentation in all surgical settings. Therefore, patients of any age without the ability to gargle safely and effectively will be excluded from the study. Patients not extubated or unable to complete gargling will be excluded from the review. Types of intervention(s)/phenomena of interest This review will consider studies that evaluate ketamine gargle (30-50 mg ketamine in 20-30 ml saline) in comparison to standard of care or placebo. Types of outcomes This review will consider studies that include the following outcome measures: reduction in the incidence of postoperative sore throat measured on a four point scale (zero-three) utilizing a direct question survey.
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