Effectiveness of intravenous lidocaine and fentanyl on attenuation of hemodynamic response to extubation for ear, nose and throat surgeries at JLNMCH, Bhagalpur, Bihar

Abstract

Background: Tracheal extubation, the purposeful removal of the endotracheal tube from the trachea, can be associated with detrimental hemodynamic and airway responses. Lidocaine and fentanyl are known to suppress hemodynamic response to extubation during Ear, nose, and throat surgeries. Smooth tracheal extubation is important after Ear, nose, and throat surgeries.Objective: To compare the effect of intravenous lidocaine and fentanyl on attenuation of hemodynamic response to extubation for Ear, nose, and throat (ENT) surgeries at JLNMCH, Bhagalpur, Bihar. Methods: This prospective cohort study recruits 74 American Society of Anesthesiologist (ASA) class I and II, age between 18 and 60 patients who underwent Ear, Nose and Throat surgeries. Unpaired T test was used to compare the mean of heart rate and mean arterial blood pressure between groups. Mann Whitney U Test was used for distribution free data. Association of categorical independent variables between two groups were analyzed using Chi Square or fisher exact test. P-values < 0.05 were considered as statistically significant with a power of 80%. Results: The demographic and clinical characteristics were comparable between groups.