Abstract

To analyze whether there is improvement in adherence to inhaled treatment in patients with COPD and asthma after an educational intervention based on the teach-to-goal method. This is a prospective, non-randomized, single-group study, with intervention and before-after evaluation. The study population included 120 patients (67 females and 53 males) diagnosed with asthma (70.8%) and COPD (29.1%). The level of adherence (low and optimal) and the noncompliance behavior pattern (erratic, deliberate and unwitting) were determined by the Test of the adherence to Inhalers (TAI). This questionnaire allows you to determine the level of adherence and the types of noncompliance. Low Adherence (LowAd) was defined as a score less than 49 points. All patients received individualized educational inhaler technique intervention (IEITI). Before the IEITI, 67.5% of the patients had LowAd. Following IEITI, on week 24, LowAd was 55% (p = 0.024). Each patient can present one or more types of noncompliance. The most frequent type was forgetting to use the inhaler (erratic), 65.8%. The other types were deliberate: 43.3%, and unwitting: 57.5%. All of them had decreased on the final visit: 51.7% (p = 0.009), 25.8% (p = 0.002), 39.2% (p = 0.002). There were no significant differences in adherence between asthma and COPD patients at the start of the study. The only predicting factor of LowAd was the female gender. An individualized educational intervention, in ambulatory patients with COPD and asthma, in real-world clinical practice conditions, improves adherence to the inhaled treatment.

Highlights

  • Chronic obstructive pulmonary disease (COPD) and asthma are conditions prone to adherence issues due to their chronic nature and to their periods of symptom remission[1].Incorrect adherence and inhaler technique reduces the treatment benefits and leads to concerns in the healthcare management and health-related consequences[2]

  • The objective of the present study is to evaluate adherence to inhaled treatment using TAI15, in real clinical practice conditions, with a cohort of ambulatory patients diagnosed with asthma and COPD; before and after an individualized educational inhaler technique intervention (IEITI)

  • A group of 160 patients was recruited for the study

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Summary

Introduction

Chronic obstructive pulmonary disease (COPD) and asthma are conditions prone to adherence issues due to their chronic nature and to their periods of symptom remission[1].Incorrect adherence and inhaler technique reduces the treatment benefits and leads to concerns in the healthcare management and health-related consequences[2]. The stated objectives include biochemical or electronic monitoring of medication administration[11] An example of these is the audio recording devices which simultaneously report on inhaler technique and adherence[12]. Most of these instruments have been designed to monitor oral medication[13,14]. The Test of adherence to inhalers (TAI)[15] has been validated for asthma and COPD. It comprises two complementary 12-item questionnaires with domains for patients and for professionals. It gathers information on the degree of adherence and patterns of noncompliance. This test correlated better with adhesion measures made with electronic devices than the Morisky-Green test[15]

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