Effectiveness of group therapy of calves for nonspecific bronchopneumonia by aerosol method

Abstract

Nonspecific bronchopneumonia of calves causes significant economic damage to farms, and therefore, it is important to develop effective therapeutic drugs, especially for group use. Aerosolbased medicines deserve attention. The purpose of the study was to investigate the effectiveness of the group aerosol method of administering the drug “Calfmin” to calves with nonspecific bronchopneumonia. Analogue calves of two to three months of age, both clinically healthy and patients with nonspecific bronchopneumonia, were involved in the experiment. Standard clinical and haematological research methods were used to determine the diagnosis and monitor the functional state of the calves’ bodies. It was found that in the blood of calves with nonspecific bronchopneumonia, an increase in the number of white blood cells was observed by 1.3 times (P<0.05) compared to clinically healthy animals. Their blood also showed an increase in the number of stab and segmented neutrophils by 2.0 times (P<0.05) and 1.6 times (P<0.01), respectively, and a decrease in the number of lymphocytes by 1.3 times (P<0.001) and eosinophils by 1.4 times (P<0.001), respectively. In sick calves, there was a 1.2-fold decrease in the number of red blood cells in the blood (P<0.001) and a 1.2-fold decrease in the haemoglobin content (P<0.001) compared to the control. An improvement in the clinical condition and haematological parameters in sick animals was recorded within 3-5 days, a reduction in the duration of therapy by 1.9-2.0 times, and 100% preservation of all sick calves