Abstract
Objective:to evaluate the effectiveness of ginge (Zingiber officinale) in reducing blood sugar and lipid levels in people with type 2 diabetes.Method:a randomized and double-blind clinical trial conducted with people with type 2 diabetes in primary care facilities. The study included individuals aged between 20 and 80 years old, using oral antidiabetic drugs and with HbA1c levels between 6.0% and 10%. The participants were paired 1:1, allocated in two distinct groups, and randomized in blocks, based on their HbA1c levels. In the experimental group, the participants used 1.2g of ginger and, in the control group, 1.2g of placebo, daily for 90 days. The primary outcome was a reduction in fasting blood sugar and HbA1c, and the secondary outcome was a reduction in lipids and HOMA-IR. 103 individuals completed the study, 47 in the experimental group and 56 in the control group.Results:the participants in the experimental group showed a greater reduction in the blood glucose and total cholesterol values compared to the control group.Conclusion:the use of ginger can help in the treatment of people with diabetes, and data support the inclusion of this herbal drug in the clinical practice of nurses. RBR-2rt2wy
Highlights
The control of type 2 Diabetes Mellitus (T2DM) has been one of the main challenges for health professionals, researchers, and people with the disease[1]
Studies analyzing the effect of ginger in the treatment of people with T2DM are still scarce and so far no publications have been found on the subject in Brazil, indicating the need for more evidence to legitimize and subsidize the inclusion of this product in the clinical practice of health professionals, mainly in Primary Health Care, as a way to facilitate the control of T2DM[12-13]
A randomized, double-blind, placebo-controlled, and parallel-group clinical trial (1:1) conducted from December 2017 to June 2018 in Primary Health Care Units (PHCUs) in Picos, in the Vale do Rio Guaribas region, state of Piauí, Brazil, with people diagnosed with T2DM
Summary
The control of type 2 Diabetes Mellitus (T2DM) has been one of the main challenges for health professionals, researchers, and people with the disease[1]. The worldwide interest in research involving the use of alternative and complementary practices has been increasing This interest is due to factors such as the search for affinities for the use of natural products; the high price of private medical assistance, together with the high cost of the medications; precarious public assistance; and the attempt to mitigate complications related to chronic diseases, such as T2DM[5-9]. In this sense, ginger appears as a promising adjuvant for the treatment of T2DM, mainly acting in the regulation of lipid metabolism, in the improvement of anti-inflammatory activities, and in the modulation of insulin release and response, with minimal adverse events and increasingly effective results[10-13]. This study aimed at assessing the effectiveness of ginger (Zingiber officinale) in reducing blood sugar and lipid levels in people with T2DM
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