Abstract
Californium-252, an isotope emitting neutrons, gamma photons and alpha particles, is being investigated for its practical use in interstitial Curie therapy. After an introduction in which the history of Californium-252 and its application in industry are described, a review of results concerning RBE values of Cf-neutrons for tolerance of different types of normal tissues and for responses of experimental tumors as a function of dose rate is given. In addition, a review of clinical results is presented.
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