Effectiveness of caffeine intake on maximal and sub-maximal physiological markers of exercise intensity among wheelchair users compared to able-bodied individuals

Abstract

The aim of the current study was to assess the effect of caffeine intake on maximal and sub-maximal physiological markers of exercise intensity and whether group (able-bodied and wheelchair users) moderated these findings. Ten able-bodied men (20.3±2.4 years, length 174.3±5.1 cm, 76.4±9.4 kg) and 9 wheelchair users (29.9±7.1 years, length 164±13 cm, 78.6±20.6 kg) participated in the study. Each participant performed 4 exercise tests. Two ramp exercise tests were used to assess the effect of caffeine intake on maximal values of power output (PO), oxygen uptake (VO2), heart rate (HR), lactate and rate of perceived exertion (RPE): one performed with 6 mg/kg body mass of caffeine ingestion as gelatine capsules, and the second one with placebo. Two constant-load exercise tests at 70% POpeak to volitional exhaustion were used to assess the effect caffeine intake on sub-maximal values of VO2, HR, lactate and RPE: one performed with 6 mg/kg body mass of caffeine ingestion as gelatine capsules, and the second one with placebo. Two way ANOVA revealed that caffeine intake does not affect maximal values of VO2, HR, lactate and RPE (P>0.05). Caffeine intake reduced sub-maximal RPE at 5 min (P<0.05) and 10 min of exercise. Sub-maximal HR at 70% POpeak was higher in caffeine than placebo among wheelchair users (P<0.05). Time to exhaustion at 70% POpeak was significantly longer in caffeine than placebo (P<0.05). VO2max and POpeak were significantly higher among able-bodied than wheelchair users (P<0.05). Caffeine has an effect on sub-maximal RPE and time to volitional exhaustion. Closed-loop exercise mode should be employed in future studies. Greater dosage of caffeine could be used but should not exceed the permitted amount of 12 mg/kg body mass. Wheelchair users should exercise and do more physical activity to enhance VO2max and POpeak.