Effectiveness of albendazole-based anti-parasitic drugs under modern conditions

Abstract

An important problem in veterinary medicine is still the control of parasitic diseases of farm and domestic animals. The market of antiparasitic drugs is widely represented by anthelmintics based on albendozole, both imported and domestic, but data on the effectiveness of these drugs are currently insufficient. The aim of the research was to determine in the comparative aspect the effectiveness of the use of antiparasitic drugs in different forms with the content of albendazole in different species of animals. In the previous stage of the studies the experimental animals were diagnosed with invasions. The most common infections in cattle were dictyocaulosis and fasciolosis; Trichostrongylus colubriformis, Cooperia oncophora, Oesophagostomum radiatum were not detected. No causative agent of Dictyocaulus vivaparus infection was detected in horses. The most common infection in dogs and cats was toxacariasis, and in mink the most common was infection wih Uncinaria spp. Along with this, no Taenia solium and Diphyllobothrium latum eggs were detected in dogs, and Opisthorchis felineus, Taenia solium, Diphyllobothrium latum were not detected in cats. After the use of preparative forms of albendazole in sick animals for 2–5 days, the presence of dead sexually mature nematodes and helminth eggs were noted in the feces of animals. The efficacy of albendazole drugs regarding helminthiasis in farm and domestic animals was 100%