Abstract
The sensorimotor diabetic polyneuropathy represents a serious health problem, as it is responsible for an increased risk of mortality and substantial morbidity, resulting from foot ulceration, amputations, and impaired quality of life. Appropriate drug treatments are often unsuccessful at providing adequate pain relief and the use of minimally invasive procedures such as spinal cord stimulation (SCS) represents a valid therapeutic choice. Patient’s medical history and characteristics as well as clinical indication for the procedure influence the clinician in choosing the right type of therapy. Here we describe two cases suffering from type 2 diabetes mellitus and sensorimotor polyneuropathy, refractory to conventional medical management: in both cases, the 10-kHz high-frequency SCS therapy led to a long-term clinically meaningful relief of symptomatology which was evaluated in terms of: complete discharge of analgesic drugs, significant reduction in the intensity of perceived pain, recovery of motor function, improvement of mood tone and sleep quality. KEY WORDS diabetic sensorimotor polyneuropathy; neuropathic pain; 10-kHz high-frequency spinal cord stimulation.
Highlights
La polineuropatia diabetica sensitivo-motoria rappresenta un grave problema di salute in quanto è responsabile di un aumento del rischio di mortalità e di una sostanziale morbilità, derivante da ulcerazione del piede, amputazioni e qualità della vita compromessa
The sensorimotor diabetic polyneuropathy represents a serious health problem, as it is responsible for an increased risk of mortality and substantial morbidity, resulting from foot ulceration, amputations, and impaired quality of life
Appropriate drug treatments are often unsuccessful at providing adequate pain relief and the use of minimally invasive procedures such as spinal cord stimulation (SCS) represents a valid therapeutic choice
Summary
Efficacia della stimolazione spinale ad alta frequenza a 10-kHz nella polineuropatia diabetica refrattaria alla terapia farmacologica: due casi clinici. Effectiveness of 10-kHz High-frequency spinal cord stimulation in diabetic polyneuropathy refractory to medical management: two case reports. Duse[2 1] UO Anestesia e terapia del dolore, Azienda Ospedaliera Universitaria Pisana. 2 Responsabile Terapia Antalgica, Azienda Ospedaliera Padova Duse[2 1] UO Anestesia e terapia del dolore, Azienda Ospedaliera Universitaria Pisana. 2 Responsabile Terapia Antalgica, Azienda Ospedaliera Padova
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