Abstract

Subjective Idiopathic Tinnitus is a common and disturbing condition characterized by an auditory perception of sound...

Highlights

  • Subjective Idiopathic Tinnitus is a common and disturbing condition characterized by an auditory perception of sound or noise that has no external source [1,2]

  • All the patients enrolled in this observational study aged more than 18 years, presented Tinnitus from minimum six months that worsened their Quality of Life (QoL) together with hearing loss

  • Note: *Legend: PTA: pure tone audiometry is the medium value in 250-500-1000-2000-4000Hz and is expressed in dB; Changing PTA: if hearing threshold medium levels changes during this six-months study; we consider a changing if there is a difference more than 10dB; Tinnitus site: the ear in which patient refers tinnitus; when patient refers bilateral, we indicated the worst side

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Summary

Introduction

Subjective Idiopathic Tinnitus is a common and disturbing condition characterized by an auditory perception of sound or noise that has no external source [1,2]. Microcirculatory disorders of the inner ear with a hemodynamic and metabolic imbalance of the endothelial leading to a damage of the cochlear cells, are often bring into play in the classical cochleovestibular symptoms such as tinnitus [4]. From the literatures seems to be clear the relationship between inner ear microcirculation dearrangements and Tinnitus: this is the reason why we try to use “an endothelial protector drug”. This pilot study aimed to evaluate the feasibility effectiveness and safety of an endothelial protector drug, such as Aminapthone, for patients with chronic idiopathic tinnitus

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