Abstract
Introduction. Endoscopic submucosal dissection (ESD) is a standard method of local excision of benign colon tumors. Nevertheless, it is not widely used because of its technical difficulty and risk of complication especially in right colon. The OBJECTIVE was to improve the results of treatment of patients with right colon neoplasms.Methods and materials. The results of 152 consecutive patients (median age 66 years, 88 female) with lateral spreading tumors (LST) were analyzed. Logistic regression was performed to evaluate risk factors of conversion and complications.Results. ESD as planned performed in 133 out of 152 patients. Conversion to bowel resection occurred in 19 cases. In the logistic regression model, lifting less than 3 mm (p=0.034) was independent risk factor of the conversion. Postoperative complications up to 30 days occurred in 5 out of 133 (3.8 %) of patients underwent ESD. There was no mortality after ESD. Severe fibrosis the base of the neoplasm was the only risk factor of postoperative complications (95 % CI=1.0—1.2; p=0.007). Final pathology revealed that 127 out of 133 patients (95.5 %) had adenomas and 6 out of 133 (4.5 %) patients had early adenocarcinomas. R0 resections was performed in 94/133 (70.7 %) cases.Conclusions. ESD is the safe and efficient method of local excision of benign right colon neoplasms. Unfavorable lifting (p=0.05) and submucosal fibrosis (p=0.007) are risk factors of ESD failure.
Highlights
Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр колопроктологии имени А
The OBJECTIVE was to improve the results of treatment of patients with right colon neoplasms
Severe fibrosis the base of the neoplasm was the only risk factor of postoperative complications
Summary
The results of 152 consecutive patients (median age 66 years, 88 female) with lateral spreading tumors (LST) were analyzed. V. Effectiveness and risk factors of endoscopic submucosal dissection for right colon neoplasms. В настоящее время эндоскопическая диссекция в подслизистом слое (Endoscopic submucosal dissection – ESD) является методом выбора для удаления доброкачественных ново образований толстой кишки [1]. Проведено проспективное обсервационное исследование, направленное на изучение результатов выполнения эндоскопической диссекции в подслизистом слое эпителиальных ново образований правой половины ободочной кишки. На базе отдела эндоскопической диагностики и хирургии проведено проспективное исследование, в которое включены 152 пациента с латерально стелящимися (LST) эпителиальными новообразованиями в правых отделах ободочной кишки. Диссекцию в подслизистом слое выполняли по установленной методике при помощи оборудования компании OLIMPUS (Япония). После удаления образования обработку его ложа производили с помощью гемостатических щипцов Сoagrasper – OLIMPUS (Япония).
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