Abstract
ABSTRACTObjective: Comorbidity with attention deficit hyperactivity disorder (ADHD) and disruptive mood dysregulation disorders (DMDD) is very common in children and adolescents In this study, we aimed to present a retrospective study of methylphenidate (MPH) treatment in 12 cases who were diagnosed with DMDD and ADHD.Method: All patients were followed-up in our outpatient clinic and the effectiveness and side effects of MPH were explored. Mood Symptom Questionnaire (MSQ-7) and Clinical Global Impression-Severity (CGI-S) were used for assessing the mood symptoms and their severity.Results: The differences between initiation time and the end-point time in CGI-S and MSQ-7 scores were statistically significant.Conclusion: In this present study, the usage of MPH was found to lead to an increase in irritability in children with ADHD and DMDD evidently.
Highlights
Attention-deficit hyperactivity disorder (ADHD) is one of the most common childhood neurodevelopmental disorders, the worldwide prevalence rate of ADHD is 5% and MPH is frequently the first choice treatment of ADHD [1]
The use of MPH increased the irritability clearly in children diagnosed with ADHD and disruptive mood dysregulation disorders (DMDD)
Irritability and temper tantrums are among core features of DMDD; due to reports from the mothers and information provided by the clinician, children’s irritability increased after MPH usage
Summary
Attention-deficit hyperactivity disorder (ADHD) is one of the most common childhood neurodevelopmental disorders, the worldwide prevalence rate of ADHD is 5% and MPH is frequently the first choice treatment of ADHD [1]. Comorbidity with ADHD and disruptive mood dysregulation disorders (DMDD) is very common in children and adolescents [2]. It is little known how DMDD symptoms affect ADHD treatment. A retrospective analysis of MPH treatment in 12 cases who were diagnosed with DMDD and ADHD was presented; they were followed-up in outpatient clinic and the effectiveness and side effects of MPH were evaluated
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