Abstract
BackgroundAcute calcific periarthritis of the hand is a relatively uncommon painful condition involving juxta-articular deposits of amorphous calcium hydroxyapatite. Although conservative treatments have been generally considered effective, there is little evidence regarding how long they could remain effective.MethodsWe retrospectively reviewed ten patients who were diagnosed with acute calcific periarthritis of the hand from January 2015 to June 2018. We recommended the use of warm baths, nonsteroidal anti-inflammatory drugs (NSAIDs), and limited activity as initial treatments. If the pain persisted despite at least 3 months of conservative treatment, we explained surgical treatment options. If the pain improved, we recommended gradual range-of-motion exercises with the continuation of daily NSAIDs use. The visual analogue scale (VAS) score for pain at each subsequent visit (3, 6, and 9 months) was compared with that of the previous visit to investigate whether the pain had decreased during each time interval. Simple radiographs taken at each visit were compared with those taken at the previous visit to determine whether any significant changes in the amount of calcification had occurred during each time interval.ResultsAll 10 patients with 17 affected joints continued conservative treatments for an average of 11.1 months. The average VAS score for pain at the initial visit was 7, while that at 3, 6, and 9 months was 4.3, 3.3, and 2.9, respectively. There was a significant reduction in the VAS score at 3 and 6 months, but not at 9 months (P values = 0.004, 0.008, and 0.598, respectively). The simple radiographs also showed a significant reduction in the amount of calcification at 3 and 6 months, but not at 9 months (P values = 0.020, 0.034, and 0.083, respectively).ConclusionsPatients with acute calcific periarthritis of the hand exhibited residual pain and calcification for a relatively prolonged period. Those who continued conservative treatment, including NSAIDs, showed pain relief and reduced calcification for up to 6 months. These results suggest that conservative treatment could be tried for at least 6 months before considering the surgical treatment of calcific periarthritis of the hand.
Highlights
Acute calcific periarthritis is an unusual and painful condition associated with juxta-articular deposits of amorphous calcium hydroxyapatite [1]
In this study, we investigated the effective period of conservative treatment, including nonsteroidal anti-inflammatory drugs (NSAIDs), for acute calcific periarthritis of the hand
Our data show that patients with acute calcific periarthritis of the hand suffered from pain for a relatively prolonged period: the average visual analogue scale (VAS) score was 4.3 at 3 months and 3.3 at 6 months
Summary
Acute calcific periarthritis is an unusual and painful condition associated with juxta-articular deposits of amorphous calcium hydroxyapatite [1]. Calcific periarthritis has many other names, such as calcific tendinitis, calcium apatite deposition disease, hydroxyapatite deposition disease, calcific bursitis, and hydroxyapatite rheumatism [2]. It can occur primarily as an idiopathic entity or as a secondary process in end-stage renal disease, collagen vascular disease, vitamin D intoxication, or tumoral calcinosis [3]. Acute calcific periarthritis of the hand is a relatively uncommon painful condition involving juxtaarticular deposits of amorphous calcium hydroxyapatite. Conservative treatments have been generally considered effective, there is little evidence regarding how long they could remain effective
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