Abstract

To compare the effective optical zones (EOZs) of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (F-LASIK) by utilizing topographic methods on the tangential curvature difference map at postoperative 1 year and to identify parameters linked to the EOZ alterations following both surgeries. Myopic patients who underwent SMILE or F-LASIK were included in the study. Patients with refractive error greater than -9.0 D sphere or -0.50 D of astigmatism were excluded from the study. EOZs were measured at postoperative 1 year by using the tangential curvature difference map of the Scheimpflug tomography system. Correlations between the EOZ alterations and relevant parameters were assessed. In total, 59 eyes in the SMILE group and 65 eyes in the F-LASIK group were assessed. The decrease in EOZ compared with the programmed optical zone was significantly higher in the F-LASIK group ( P < 0.001). The increase in corneal asphericity was significantly relevant to the decrease in EOZin both groups according to the multiple regression analysis ( P < 0.001, B/95% CI: 0.62/0.34 and 0.90, standardized-Beta: 0.587 for the SMILE group; P < 0.001, B/95% CI: 0.74/0.41 and 1.07, standardized-Beta: 0.631 for the F-LASIK group). The EOZ decreased 1 year after both SMILE and F-LASIK. The SMILE group showed less EOZ reduction than F-LASIK patients relative to the programmed optical zone. The decrease in EOZ was correlated with the increase in corneal asphericity in both groups.

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