Abstract
Effective Mass Layer of a Single Drop of Liquid Located on a Quartz Crystal Microbalance
Highlights
Quartz crystal microbalances (QCMs) have recently attracted much attention as promising label-free, inexpensive, and highly sensitive microsensors capable of performing in liquid environments.[1,2,3] Commonly used in practical applications are the AT-cut quartz crystal resonator in which thickness-shear vibrations are excited to set up standing waves
QCMs are typically investigated for sensor applications in which one surface of a QCM is completely immersed in a Newtonian liquid, or usually used as a core detector to build a flowinjection-analysis system in many biochemical research studies, but the viscous damping in liquids would cause large frequency shifts and large losses in the quality factor Q leading to instability and even cessation of oscillation
The minimum reflection frequency of the QCM without loading is 9989225 Hz
Summary
Quartz crystal microbalances (QCMs) have recently attracted much attention as promising label-free, inexpensive, and highly sensitive microsensors capable of performing in liquid environments.[1,2,3] Commonly used in practical applications are the AT-cut quartz crystal resonator in which thickness-shear vibrations are excited to set up standing waves. Recent research studies using QCMs have demonstrated wide applications of this ultrasensitive sensor in various areas of science and technology.[4,5,6,7,8,9,10,11] The linear relationship between the mass change and the resonance frequency shift of a QCM is described using the Sauerbrey equation.[12] Kanazawa developed an improved model to describe the response of a QCM performing in a Newton liquid.[13]. QCMs are typically investigated for sensor applications in which one surface of a QCM is completely immersed in a Newtonian liquid, or usually used as a core detector to build a flowinjection-analysis system in many biochemical research studies, but the viscous damping in liquids would cause large frequency shifts and large losses in the quality factor Q leading to instability and even cessation of oscillation. In many research studies, QCMs were loaded with a droplet of liquid instead of being immersed in a sample liquid.[17,18,19,20,21,22]
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