Abstract
Background: Nosocomial infection raises a serious public health problem, as indicated by large mortality rates of representative nosocomial pathogens such as methicilin-resistant Staphylococcus aureus (MRSA) and recent community and world-wide outbreaks of influenza and severe acute respiratory syndrome involving community hospitals. Epidemic modeling for general communities based on contact networks of individuals is a powerful tool for understanding those large-scale epidemic outbreaks. However, disease propagation may occur in health care facilities in a manner different from in a community because of different contact patterns in the two situations.
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