Effective chemotherapy of an abdominal liposarcoma

Abstract

L I P O S A R ( 3 0 M A i s a n extremely u n c o m m o n t umor in children. K a u f f m a n and Stout 1 in 1959 found 15 wel l -documented cases in the l i te ra ture and a d d e d 13 cases which they had seen in consul ta t ion over a thir ty year period. I n 1960, Enter l ine and associates, 2 reviewed the experience with this tumor a t the Univers i ty of Pennsylvania Hospi ta l and the Presbyter ian HospitM (Phi ladelphia) dur ing the per iod f rom 1940 to 1957. Of a to ta l of 53 cases only 3 were inpat ients under 20 years of age. Ti le t r ea tment of choice for pat ients with resectable l iposarcomas is wide surgical excision.a, 2 W h e n this can be done, there is an excellent possibility of comple te eradicat ion of the mal ignancy. I f complete surgical excision is not possible, rad ia t ion therapy may offer pa l l ia t ion and occasionally will result i n longterm survival? The fol lowing is a repor t of a child with an abdomina l l iposarcoma who was t reated wi th chemotherapeut ic agents following unsuccessful surgical excision and radia t ion therapy. T h e appa ren t successful outcome in this pa r t i cu la r pa t i en t suggests tha t this ap-