Abstract
Osteoarthritis (OA) results from an imbalance of anabolism and catabolism in the joint, which may be influenced by the biological and mechanical environment. Excessive forces in specific regions of the joint surfaces and alterations in tissue responses, leading to the development of osteoarthritis are also exacerbated with abnormal loading of the knee joint due to overweight or a joint disorder [1-3].
Highlights
Osteoarthritis (OA) results from an imbalance of anabolism and catabolism in the joint, which may be influenced by the biological and mechanical environment
In terms of the Short Form – 36 Version 2 (SF-36v2) Social Functioning and Pain sub scores, there was no change in score for the placebo group (d = 0.00), while the active group noticed an improvement by small (d = -0.34) and medium (d = -0.50) amounts, respectively
While for the SF-36v2 Emotional Well-Being and General Healthy Issues sub scores, the placebo-based subjects dis-improved over the 8 weeks (d = 0.07 and 0.15, respectively), while the subjects in the active group improved in both cases (d = -0.18) and -0.09, respectively)
Summary
Osteoarthritis (OA) results from an imbalance of anabolism and catabolism in the joint, which may be influenced by the biological and mechanical environment. As the number of elderly people increases, osteoarthritis represents a major economic burden on the health care systems and is a serious threat to the quality of life within the populations. Potential effects of different doses of specific fish collagen peptides (Naticol®) on the signs of skin ageing were firstly assessed in double-blind, randomised and placebo controlled clinical studies. The studies showed benefits of fish collagen peptides (Naticol®) on skin firmness, skin hydration and wrinkle appearance. In addition to these benefits, some animal experiments have suggested that ingestion of specific fish collagen peptides (Naticol®) might have beneficial effects on joint health such as osteoarthritis
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