Abstract
The effects of parathyroid hormone on serum calcium and alkaline phosphatase in the chicken were studied. The injection of parathyroid extract (Eli Lilly) at the dosage level of 500 U. S. P. units per kg body weight into 13-week-old pullets significantly increased serum calcium concentration 4 hrs. after the injection, but did not change the level of serum alkaline phosphatase. The injection of 100 U. S. P. units parathyroid extract per kg body weight into 13-week-old cockerels and pullets induced changes neither in serum calcium level nor in serum alkaline phosphatase level.The injection of the suspension of desiccated beef parathyroid powder at the dosage levels of 25 to 50 U.S.P.units per kg body weight into 13-week-old cockerels had no effect on serum calcium concentration, but significantly reduced the level of serum alkaline phosphatase. The injection of 0.5g mash diet suspended in distilled water into 13-week-old cockerels induced a significant reduction of the serum level of alkaline phosphatase.These results indicate that the parathyroid hormone itself has no effect on serum level of alkaline phosphatase, and the detrimental effects such as the injection of unabsorbable insoluble materials reduce the level in the chicken.
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