Effect on liver and serum lipids in rats of dietary additions of fibers and cholestyramine to a cystine-excess diet.

Abstract

Feeding a cystine-excess diet caused growth retardation, hepatomegaly and hypercholesterolemia. Studies were undertaken to examine whether some dietary fibers and cholestyramine could prevent the hypercholesterolemia induced by feeding a cystine-excess diet for 6 days. Of the dietary additions tested, carrageenan, chitin, chitosan, cholestyramine, guar gum, konjac mannan, locust bean gum, tamarind gum, tra gum and xanthan gum were effective in preventing hypercholesterolemia.