Abstract
Objectives To examine the usefulness of an absorbable hemostatic gelatin sponge for hemostasis after transrectal prostate needle biopsy.Subjects and Methods The subjects comprised 278 participants who underwent transrectal prostate needle biopsy. They were randomly allocated to the gelatin sponge insertion group (group A: 148 participants) and to the non-insertion group (group B: 130 participants). In group A, the gelatin sponge was inserted into the rectum immediately after biopsy. A biopsy-induced hemorrhage was defined as a case in which a subject complained of bleeding from the rectum, and excretion of blood clots was confirmed. A blood test was performed before and after biopsy, and a questionnaire survey was given after the biopsy.Results Significantly fewer participants in group A required hemostasis after biopsy compared to group B (3 (2.0%) vs. 11 (8.5%), P=0.029). The results of the blood tests and the responses from the questionnaire did not differ significantly between the two groups. In multivariate analysis, only “insertion of a gelatin sponge into the rectum” emerged as a significant predictor of hemostasis.Conclusion Insertion of a gelatin sponge into the rectum after transrectal prostate needle biopsy significantly increases hemostasis without increasing patient symptoms, such as pain and a sense of discomfort.
Highlights
Transrectal ultrasound (TRUS)-guided prostate biopsy is a standard procedure for the diagnosis of prostate cancer
While the gelatin sponge can be expected to promote hemostasis in rectal bleeding, there are no studies evaluating its efficacy on hemostasis in transrectal ultrasound-guided prostate biopsy
From October 2011 to November 2012, after ibju | absorbable hemostatic gelatin sponge after transrectal prostate needle biopsy informed consent, a total of 278 participants were submitted to a transrectal ultrasound-guided prostate biopsy with an 18G×200mm biopsy needle under local anesthesia by the same surgeon (K.K)
Summary
Transrectal ultrasound (TRUS)-guided prostate biopsy is a standard procedure for the diagnosis of prostate cancer. It is generally a safe procedure with minimal complications including rectal and genitourinary lesions. Rectal bleeding is one of the most common side effects of TRUS-guided prostate biopsy. Excessive bleeding is rare, it can occur and hemostasis is essential. The utility of the absorbable hemostatic gelatin sponge for hemostasis in anorectal surgery has been reported [1, 2]. While the gelatin sponge can be expected to promote hemostasis in rectal bleeding, there are no studies evaluating its efficacy on hemostasis in transrectal ultrasound-guided prostate biopsy
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Schedule a callMore From: International braz j urol : official journal of the Brazilian Society of Urology
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