Abstract
a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.
Highlights
Prostate cancer (PCa) is a leading cause of death in men in the developing countries.[1]
The signaling cascade of autocrine/paracrine growth factors plays an important role in promoting prostate cancer cells growth, survival, migration, and progression
The objective of the present study is to determine the inhibitory effect of α-terpinene, -caryophyllene, linalool, luteolin, and quercetin on the viability, adhesion, migration and invasion of PCa cells
Summary
Prostate cancer (PCa) is a leading cause of death in men in the developing countries.[1]. PCa is hormonedependent, and can be controlled using the hormone-ablation therapy that suppresses the rate of PCa growth. The cancer overcomes its hormone-dependence in advanced stages leading to castration-resistant PCa that can metastasize to the lungs, liver and bones.[6] Conventional chemotherapy has poor outcome and causes severe side effects. Testing plant extracts and natural products has been widely practised in the pharmaceutical industry. It has been a valuable source of drug leads for many years.[7] Numerous in vitro studies have been conducted to explore the cytotoxic or chemopreventive activity of naturallyoccurring compounds and identify their respective molecular mechanisms of action
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