Abstract
A safe reduction of the recovery period of anaesthetized animals is desired to minimize risks of complications. To study the effect of yohimbine on the recovery time after general anaesthesia with a xylazine-thiopental regime, a total of 30 Creole goats were divided randomly into three groups of ten goats each, receiving either normal saline (group A), 0.2% yohimbine solution 0.125 mg/kg (group B), or 0.250 mg/kg (group C). Anaesthesiological (mean arousal time and mean standing time) and physiological (respiratory rate, heart rate and rectal temperature) values were established and evaluated to assess the effect of the treatment. It was found that yohimbine significantly ( P < 0.05) decreased the mean arousal time and the mean standing time, however, there was no difference between the doses used. In addition, yohimbine significantly ( P < 0.05) increased the respiratory rate, and the heart rate (group C only), with no effect on the rectal temperature. It was concluded that yohimbine had an antagonistic effect on the CNS-depressant state induced by xylazine-thiopental anaesthesia in goats.
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