Abstract
Present study was aimed to assess effect of walnut kernel with different dose on individuals with hyperlipidemia. Study was conducted at Fatima Memorial Hospital (FMH), Shadman, Lahore, Pakistan and 90 hyperlipidemic individuals were divided into 3 groups having no other disease. Total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were estimated in all three groups on 0 day (at start) 30th day and on 56th day of study. A significant (p < 0.05) result was observed and blood lipid profile of individuals were seen to improve by consuming walnuts. Group B who were fed 25 g walnuts kernel per day for 56 days a decrease of 21.6% in serum TC, 28.9% in serum TG, 26.5% in LDL-C; and an increase of 27.1% in HDL-C was observed as compared to control group. Whereas group C individuals who were fed 50 g walnut kernel per day showed a decrease of 30.3% in serum TC, 37.2% in serum TG, 33.8% in LDL-C and an increase of 50.0% in HDL-C was observed. It was concluded that consumption (25 g and 50 g) of walnut kernel showed significant (p < 0.05) improvements in lipid profile of hyperlipidemic individuals when consumed for 56 days.
Highlights
A major risk factor for coronary heart disease (CHD) and atherosclerosis is hyperlipidemia which is prevalent in a significant proportion in the adult population
Between 11.7% to 41.2% adults aged 20-39 and 40-64 years respectively were found to have high levels of low density lipoprotein cholesterol (LDL-C) but 10.6% (20-39 years) and 47.7% (40-64 years) adults who had hyperlipidemia were being treated according to the National Health and Nutrition Examination Survey (NHANES) (Pencina et al, 2014)
Cardiovascular diseases are a cause of death worldwide and dyslipidemia is one of the risk factor
Summary
A major risk factor for coronary heart disease (CHD) and atherosclerosis is hyperlipidemia which is prevalent in a significant proportion in the adult population. Tree nuts are dietary constituents that are known to improve lipid profile and among the tree nuts walnuts are the most common nuts consumed in the world (Hayes et al, 2016). Consumption of tree nuts lowered the body mass index and improve the lipid profile of the adults in a recent study done in the United States (O’Neil et al, 2015). Walnut efficacy in hyperlipidemic adults can help to improve triglyceride levels and elevate high density lipoprotein (HDL) cholesterol, which is known to be the good cholesterol anticoagulant properties are another specialty of the omega-3 fatty acid (Taj et al, 2010). This study was designed to see the effect of walnut consumption on lipid profile of hyperlipidemic patients as walnut is available in our community and liked by all age groups
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