Abstract

Objectives: Lipid deposition in the extraadipose tissue, mostly in the liver and muscle is one of the most serious factor associated with obesity and metabolic syndrome (MS). More important than total amount of tissue lipids is their composition, mostly the properties of fatty acids and quantity of lipotoxic intermediates (ceramides and diacylglyceroles). The positive role of physical activity on the obesity-related disorders is well documented but its effect on membrane fatty acid composition and concentration of lipotoxic intermediates is unclear.

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