Effect of vitreolysis and lecithin-bound iodine in the treatment of different course of vitreous opacities

Abstract

Objective To evaluate the clinical effect of vitreolysis and lecithin-bound iodine in the treatment of different course of vitreous opacities. Methods Retrospectively analyzed the 287 patients (370 eyes) with vitreous opacity. All the patients underwent visual acuity, intraocular pressure, slit lamp, fundus examination, ultrasound examination of mydriasis, exclusion of vitreous body inflammatory diseases, retinal lesions. The patients with vitreous opacities were divided to group A, group B, group C, group D according to the course of the disease, and that the course of group A and group B was less than two months, the course of group C and group D was more than two months but less than two years. The patients of group A and group C were treated by Neodymium Yttrium Aluminm Garnet(Nd: YAG)laser, the patients of group B and group D were treated by lecithin-bound.The changes of vision and vitreous opacities were observed by slit-lamp microscopy, eye ground examination and B ultrasonic examination before and after treatment, the vitreous body turbidity grade was evaluated. Results According to the questionnaire score, the symptom improvement degree was divided into no improvement (1-2 points), partial improvement (3-5 points), and significant improvement (6-10 points). At 1 month after treatment, group A: no improvement in 5 eyes(5.9%), partial improvement in 15 eyes(17.6%) and significant improvement in 65 eyes(76.5%); group B: no improvement in 13 eyes(13.7%), partial improvement in 30 eyes(31.6%) and significant improvement in 52 eyes(54.7%); group C: no improvement in 8 eyes(8.2%), partial improvement in 19 eyes(19.6%) and significant improvement in 70 eyes(72.2%); group D: no improvement in 35 eyes(37.6%), partial improvement in 48 eyes(51.6%) and significant improvement in 10 eyes(10.8%). All the patients had no complications. Conclusions The Nd: YAG laser can detroy the vitreous floaters, make them easier to be absorbed and obviously improve the visual acuity, which is a effective way to treat vitreous floaters. Lecithin iodine is effective in the treatment of vitreous opacity with short onset time, but it is not effective for old vitreous opacity. Key words: Vitreous opacity; Neodymium Yttrium Aluminm Garnet laser; Vitreolysis; Lecithin-bound iodine