Abstract
SummaryThe gonadotrophin content of the anterior pituitary taken from vitamin-E deficient rats, 315 to 469 days of age, was determined. The weights of testes, seminal vesicles and anterior prostates of groups of male rats hypophysectoniized at 21 dtays of age and subsequently injected with suspensions of frozen-dried anterior pituitaries were compared. The testes of the hypophysecto-mized rats which received the pituitary suspension from vitamin-E deficient male or female rats were significantly heavier than those of rats which received pituitary powder from the controls. There was no difference in the weights of the seminal vesicles or anterior prostates.It is concluded that the gonadotrophin content of the anterior pituitary gland is elevated in older vitamin-E deficient male and female rats. The relationship of these findings to the changes in the gonads in vitamin-E deficiency are discussed.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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