Effect of vitamin B12b injections on the growth of young Merino sheep

Abstract

In two experiments near Robe in the south-east of South Australia, on soil highly prone to the occurrence of cobalt deficiency in sheep, the effect of injections of vitamin B12b (hydroxocobalamin) on grossly cobalt-deficient weaner sheep and suckling lambs was compared with the effect of oral doses of cobalt as liquid drenches or ruminal pellets. All the supplements used were effective in treating cobalt-deficient weaned sheep or preventing the onset of cobalt deficiency in lambs. A single injection of vitamin B12b (1 mg), under the conditions of these experiments, satisfied the requirements of lambs for 14 weeks and cobalt-deficient weaner sheep for up to 40 weeks. The use of vitamin B12b in preventing or correcting cobalt deficiency in sheep in the field is discussed. Serum vitamin B12b concentration was not a reliable indicator of the vitamin B12b status of young sheep which had been given single injections of vitamin B12b. Vitamin B12b, deficiency in sheep was associated withdecreased concentrations of blood haemoglobin and of glucose, total proteins, urea and cholesterol in blood serum. The activities of serum aspartate transminase and alkaline phosphatase did not appear to be affected by the vitamin B12b status of the sheep.