Effect of Visceral Fat Index on Perioperative Efficacy of Laparoscopic Radical Resection for Colorectal Cancer

Abstract

Purpose: To investigate the effect of visceral fat index (VAI) on perioperative period after radical resection of colorectal cancer, and analyze the relationship between VAI and postoperative complications. At the same time, we also discussed whether the correlation between VAI and complications is superior to body mass index (BMI), waist circumference (WC), triglyceride (TG), high-density lipoprotein (HDL) and other common body fat indicators.
 Methods: From October 2021 to June 2022, 178 colorectal cancer patients in the Gastrointestinal Surgery Department of the First Affiliated Hospital of Chongqing Medical University were collected. Various indexes of patients were obtained through preoperative physical examination and blood examination. VAI value was calculated by formula, because of the high triglyceride-waist-circumference phenotype (increased waist circumference and hypertriglyceridemia) and visceral fat index (Vai, assessed according to waist circumference, body mass index, triglyceride and high-density lipoprotein cholesterol) , it is considered a cheap and effective marker for visceral (intra-abdominal) obesity and metabolic disorders. and then divided into groups according to dichotomy. Because the visceral index grade was divided into a total of 30 grades, according to grade, into the high VAI value group (VAI grade more than 15 grades) and the low VAI group (no more than 4 grades), with 89 patients in the high VAI group; There were 89 patients in the low VAI group. The relationship between VAI value and postoperative complications of patients was discussed by using statistical methods, and whether it was better than other body fat indexes was further analyzed.
 Results: 178 patients met the inclusion criteria and were divided into 89 patients in the high VAI group and 89 patients in the low VAI group according to the dichotomy. In patients with high VAI value, the operation time was significantly prolonged (213.01 ± 63.67 vs 190.34 ± 68.69 p=0.02), and the tumor N stage was higher (p=0.04). The results of ROC curve revealed that the area under the curve of VAI value was larger than that of BMI, waist circumference, triglyceride and high-density lipoprotein, suggesting that the value of VAI value was higher in diagnosis.
 Conclusions: The increase of VAI can prolong the operation time of colorectal cancer patients undergoing radical surgery, affect the recovery of the body after surgery, and increase the risk of complications. At the same time, compared with BMI, waist circumference, triglyceride and high-density lipoprotein, VAI has a better prediction effect on complications, which can be popularized in clinical work.