Effect of vesicle size, polydispersity and multilayering on solid state 31P- and 2H-NMR spectra

Abstract

In this paper, we investigate upon the effect of isotropic motions on 31P- and 2H-NMR spectral lineshapes. The effect of size, polydispersity and number of bilayers in tumbling vesicles is taken into account by considering both the rotational diffusion of the small structure and the lateral diffusion of a molecule on the curved surface. Spectral simulations considering quadrupolar or chemical shift anisotropy interactions show that spectral lineshapes are very sensitive to the above parameters and may be used to probe size and polydispersity of unilamellar vesicles or to determine the number of bilayers and the size of the inner water core of multilamellar vesicles.