Abstract
IN this issue of ANESTHESIOLOGY, Marin-Corral et al. 1 report a reduction of several markers of oxidative and nitroxidative stress in the diaphragm and limb muscles of rats exposed to ventilator-induced lung injury (VILI). This finding initially seems counterintuitive because VILI is thought to induce a systemic inflammatory state, 2 which should lead to increased, rather than decreased, oxidative stress also in tissues other than the lung. In this editorial, we will briefly review the basic biochemistry of the oxidative markers measured by Marin-Corral et al. to provide some context to these observations, highlight the main results of this study, and define a framework for future investigations of the skeletal muscle effects associated with VILI.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
