Abstract
PREVIOUS observations on the effect of vasopressor substances on the thoracic duct lymph flow have been summarized by Haynes1 and Ruscynyak et al.2. However, there is still a certain amount of disagreement in the literature and previous investigations have only shown changes in lymph flow rate without recording blood pressure. Recently adrenaline3,4 and noradrenaline3 were observed to stimulate the thoracic duct lymph flow in dogs. An increase in lymph flow rate following administration of angiotensin was also demonstrated in our laboratory5. The mechanism underlying the lymph production due to vasopressor substances, however, is not completely understood. The present communication reports experiments carried out on rats in which the effects of various vasopressor substances on thoracic duct lymph flow were studied and compared.
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