Abstract

Effect of vasopressin on sodium transport in renal cortical collecting tubules. Electrical potential difference (PD) and sodium (Na) flux were measured in isolated perfused renal cortical collecting tubules of rabbits. Vasopressin caused a transient increase in PD and net Na flux (lumen to bath), without any change in the back flux of Na (bath to lumen). We conclude that active Na transport is augmented by vasopressin in the collecting tubule, similar to the effect previously observed in anuran membranes.

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