Abstract
Both epinephrine and phenylephrine are capable of prolonging the duration of anesthesia when added to solutions of tetracaine intended for intrathecal use. Conflicting data exist concerning the relative efficacy of vasoconstrictor agents added to lidocaine and bupivacaine solutions intended for intrathecal use. The present investigation was initiated to study the comparative efficacy of epinephrine and phenylephrine in combination with tetracaine, lidocaine, and bupivacaine employing a model for spinal anesthesia in the dog. The results indicate that epinephrine and phenylephrine are capable of significantly prolonging the duration of motor blockade induced by tetracaine in the dog. When compared to plain solutions, no significant prolongation of motor blockade was observed following intrathecal administration of either lidocaine or bupivacaine with epinephrine and phenylephrine.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
